The Prevalence of Human Papillomavirus and Its Impact to Cervical Dysplasia in the Northwest Territories

Regions: Inuvialuit Settlement Region, Gwich'in Settlement Area, Sahtu Settlement Area, Dehcho Region, North Slave Region, South Slave Region

Tags: health, health care evaluation, sexually transmitted infection, women's health

Principal Investigator: Mao, Yang (2)
Licence Number: 14335
Organization: Public Health Agency of Canada
Licenced Year(s): 2009 2008
Issued: Apr 23, 2008
Project Team: Dr Paul Brassard (Co_Principal Investigator, McGill University), Dr Ying Jiang (Co-ordinator, PHAC), Dr Anita Li (Co-ordinator, PHAC), Dr Bing Guthrie (Partner, Stanton Territorial Health Authority), Dr Alberto Severini (Partner, PHAC), Dr andre Corriveau (Partner, DHSS, GNWT), Ms Marie Deseules (Partner, PHAC), Susan Chatwood (Local Co-ordinator, Arctic Health Research Network)

Objective(s): The primary objective of this study is to determine the prevalence of the Human Papillomavirus (HPV) infection and cervical dysplasia in women of the Northwest Territories using a DNA technology (HPV-DNA Test). The study will also aim to determine whether cervical cancer screening programs should include the use of the HPV-DNA test to increase effectiveness of cervical cancer screening.

Project Description:

The primary objective of this study is to determine the prevalence of the Human Papillomavirus (HPV) infection and cervical dysplasia in women of the Northwest Territories using a DNA technology (HPV-DNA Test). The study will also aim to determine whether cervical cancer screening programs should include the use of the HPV-DNA test to increase effectiveness of cervical cancer screening.

This will be an unlinked anonymous study where all PAP smears performed in the Northwest Territories will be analyzed and tested for specific HPV types. Specimens will be sent to the Dynacare Kasper Laboratories in Edmonton and then to the National Microbiology Lab in Winnipeg. The researchers expect to obtain the results from PAP tests over 3 years. They will notify the people in the Northwest Territories through the Health Centres and Clinics as well as through the media (newspaper, television and radio). Patients will be given the option to opt out of the project.

A Report will be written which will be available to all the communities. The information will also be available on the website of the Department of Health and Social Services as well as in their publications.

Fieldwork will be conducted from April 23 to December 31, 2008, at all the community health centres, medical clinics, and hospitals within the Northwest Territories.